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Bioinformatics Specialist

Kevin Bradley

Education

  • BS in Recombinant Genetics and Computer Science. Western Kentucky University (2000)

Role at the Foundation

  • Software Engineering. As a cutting-edge research organization, the FfAME requires custom software that can perform duties such as unique primer creation, sequence analysis, and analysis of large amounts of biological data. I am in charge of creating this software, as well as maintaining a large-scale database to house both internally and externally created data that is integral to our research.
  • Data Analysis. Working with the scientists at FfAME, I assist in analyzing data using custom-made and 3rd-party tools. This includes such data as high-throughput sequencing, protein heterogeneity, and pathogen strain relatedness.
  • IT Management. Serving as the Foundation's IT manager, I am responsible for the setup and maintenance of the Foundation.s servers, as well as a 16-node computer cluster. I am also tasked with assisting FfAME employees with personal workstation setup, software installation, and troubleshooting any computer-related issues.

Recent Publications

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Ultra-rapid detection of SARS-CoV-2 in public workspace environments
Yaren, O., McCarter, J., Phadke, N., Bradley, K. M., Overton, B., Yang, Z., Ranade, S., Patil, K., Bangale, R., Benner, S. A.
PLOS One , Public Library of Science (2021) 10.1371/journal.pone.0240524, DOI:10.1101/2020.09.29.20204131
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Eliminating Primer Dimers and Improving SNP detection using Self-Avoiding Molecular Recognition Systems (SAMRS)
Yang, Z., Le, J.T., Hutter, D., Bradley, K.M., Overton, B.R., McLendon, C., Benner, S.A.
Biol. Methods Protoc. , Oxford Academics (2020) 5(1):bpaa004, DOI:10.1093/biomethods/bpaa004
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Multiplexed kit based on Luminex technology and achievements in synthetic biology discriminates Zika, chikungunya, and and four serotypes of dengue viruses in mosquitoes.
Glushakova, L.G.. Alto, B.W., Kim, M.-S., Hutter, D., Bradley, A., Bradley, K.M., Burkett-Cadena, N.D., Benner, S.A.
BMC Infect. Dis. , BioMed Central Ltd. (2019) 19:418, DOI:10.1186/s12879-019-3998-z
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Multiplexed isothermal amplification based diagnostic platform to detect Zika, chikungunya, and dengue-1.
Yaren, O., Alto, B. W., Bradley, K. M., Moussatche, P., Benner, S. A.
J. Vis. Exp. , JoVE (2018) 133: e57051, DOI:10.3791/57051
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Nucleoside analogs to manage sequence divergence in nucleic acid amplification and SNP detection.
Yang, Z., Kim, H.-J., Le, J., McLendon, C., Bradley, K.M., Kim, M.-S., Hutter, D., Hoshika, S., Yaren, O., Benner, S.A.
Nucl. Acids Res. (2018) 46(12): 5902-10,DOI:10.1093/nar/gky392
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Point of sampling detection of Zika virus within a multiplexed kit capable of detecting dengue and chikungunya
Yaren, O., Alto, B.W., Gangodkar, P.V., Ranade, S.R., Patil, K.N., Bradley, K.M., Yang, Z., Phadke, N., Benner, S.A
BMC Infect. Dis. , BioMed Central Ltd. (2017) 17(1):293, DOI:10.1186/s12879-017-2382-0
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Synthesis and Enzymology of 2'-Deoxy-7-deazaisoguanosine Triphosphate and Its Complement: A Second Generation Pair in an Artificially Expanded Genetic Information System
Karalkar NB, Leal NA, Kim MS, Bradley KM, Benner SA
ACS Synthetic Biology , American Chemical Society (2016) doi: 10.1021/acssynbio.5b00276
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Aptamers against Cells Overexpressing Glypican 3 from Expanded Genetic Systems Combined with Cell Engineering and Laboratory Evolution
Zhang, L, Yang, Z, Trinh, TL, Teng, I-T, Wang, S, Bradley, KM, Hoshika, S, Wu, Q, Cansiz, S, Rowold, DJ, McLendon, C, Kim, M-S, Wu, Y, Cui, C, Liu, Y, Hou, W, Stewart, K, Wan, S, Liu, C, Benner, SA, Tan, W
Angew. Chem. Int. Ed. 55 (2016) doi: 10.1002/anie.201605058
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Standard and AEGIS nicking molecular beacons detect amplicons from the Middle East respiratory syndrome coronavirus
Ozlem Yaren, Lyudmyla G. Glushakova, Kevin M. Bradley, Shuichi Hoshika,Steven A. Benner
J Virol Methods (236) , Elsevier 54-61 (2016) doi:10.1016/j.jviromet.2016.07.008
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A norovirus detection architecture based on isothermal amplification and expanded genetic systems
Ozlem Yaren, Kevin M. Bradley, Patricia Moussatche, Shuichi Hoshika, Zunyi Yang,Shu Zhu, Stephanie M. Karst, Steven A. Benner
J Virol Methods (237) , Elsevier 64-71 (2016) doi: 10.1016/j.jviromet.2016.08.012
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